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Welcome to the Best Hotel in Jacksonville, Florida The Holiday Inn Express Hotel & Suites Jacksonville - South places visitors near the area's top businesses and attractions, including Mayo Clinic, and EverBank Field. Since our hotel's located in Jacksonville, FL, you'll be near numerous area businesses, including Southpoint Business Park, Deerwood Office, Cypress Point Office Park, Brooks Rehabilitation Hospital, and the Mayo Clinic. The beaches are only a short drive away. Our modern facilities boast a Business Center, which offers print and copy services, as well as computer access. You can also take advantage of the 825-sq-ft meeting room if you need to host a meeting while in the area. The Holiday Inn Express® hotel in Jacksonville, Florida places you near area attractions like Drew Park and St. Johns Town Center. Other nearby attractions include Dave & Buster's Restaurant and huge video arcade for the whole family! Come watch an exciting Jaguars' game at Everbank Field. We proudly offer a sparkling, outdoor pool and Fitness Center for your convenience. Thanks to the free high-speed Internet access throughout the hotel, it's easy to stay connected. We serve 24-hour coffee and tea and offer a complimentary hot breakfast bar every morning.