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Enjoy comfort and convenience at our Holiday Inn Express in Winston Salem NC. Located within close proximity to Wake Forest Baptist Medical Center, our hotel offers more than just a home away from home for medical center patients, families and traveling employees. Business travelers will also be impressed by the comfort of our Winston-Salem hotel. Situated downtown near the Benton Convention Center and Innovation Quarter, we are convenient to large companies, including Inmar, Reynolds American, Wells Fargo, and Wake Forest Baptist Medical Center. While lodging here, guests enjoy a central location that is close to many shops and restaurants within walking distance. We enjoy serving our guests traveling to local colleges, such as Winston-Salem State University, Wake Forest School of Medicine and Salem College. Our hotel features an outdoor seasonal pool, and 24-hour fitness center for your enjoyment. We also have an on-site laundry room, and every morning we treat our hotel guests to a free, hot breakfast bar. In Winston-Salem, NC, you will find a “home away from home” at our Holiday Inn Express hotel. Book your reservation now to take advantage of our great Winston-Salem hotel deals and rates. We look forward to greeting you!